Thursday, October 4, 2012

Permira takes the lead in Ancestry sale talks: sources

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Ancestry is focusing its discussions on Permira after it asked the private equity firm and its competitors - Hellman & Friedman LLC and TPG Capital LP - to improve on their offers, the people said. 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Source: http://news.yahoo.com/permira-takes-lead-ancestry-sale-talks-sources-174629701--sector.html

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Tuesday, October 2, 2012

Health care access continues to shrink in Texas (Offthekuff)

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Sanofi says Lyxumia diabetes drug studies positive

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Clam shells yield clues to Atlantic?s climate history

ScienceDaily (Oct. 1, 2012) ? Two Iowa State University graduate students are just back from the Gulf of Maine with another big catch of clam shells.

Shelly Griffin and Madelyn Mette recently boarded a lobster boat, dropped a scallop dredge into 30 meters of ocean water and pulled up load after load of Arctica islandica.

?These are the clams that end up in clam chowder,? said Alan Wanamaker, an assistant professor of geological and atmospheric sciences in the College of Liberal Arts and Sciences. Wanamaker studies paleoclimatology, the variations and trends of past climates and environments, with the goal of better understanding future climate changes.

The Iowa State researchers only need a few live, meaty clams for their studies. They?re really after the old, dead shells. Off the coast of Maine, clams can live up to 240 years, year after year adding another band to their shells, just like a tree adds another growth ring. In the colder waters of the North Atlantic near Iceland, the clams can live up to 500 years, recording even more information in what scientists call annual shell increments.

Wanamaker and his research team bring those shells back to Iowa State?s Stable Isotope Laboratory where they?re cleaned, sorted, measured, cut, polished, drilled and otherwise prepared for careful microscopic imaging, geochemical testing and radiocarbon analysis.

It turns out those shell increments are a lot like sensors at the bottom of the ocean ? they record long records of information about the ocean, including growing conditions, temperatures and circulation patterns.

A paper published by Nature Communications in June 2012 reported how Wanamaker (the lead author) and an international team of researchers used radiocarbon data from shells to determine when clams collected north of Iceland were living in ?young? or ?old? water. Young water had been at the surface more recently and probably came from the Atlantic. Old water had been removed from the surface much longer and probably came from the Arctic Ocean.

The paper reports warmer, younger water from the Gulf Stream during the warmer Medieval Climate Anomaly from about A.D. 950 to 1250. The paper also reports that shell data showed older, colder water during Europe?s Little Ice Age from about A.D. 1550 to 1850.

The researchers? interpretation of the data says the Gulf Stream carrying warm water from the subtropical Atlantic was strong in the medieval era, weakened during the Little Ice Age and strengthened again after A.D. 1940. Those fluctuations amplified the relative warmth and coolness of the times.

Wanamaker said a better understanding of the ocean?s past can help researchers understand today?s climate trends and changes.

?Is the natural variability only that, or is it influenced by burning fossil fuels?? he said. ?Maybe we can understand what will happen in the next 100 years if we understand oceans over the past 1,000 years.?

And so Wanamaker ? a former high school science teacher in Maine whose fascination with climate change sent him back to graduate school ? works with students to carefully collect, process and study clam shells.

The research is painstaking ? the shell increments are measured in millionths of a meter and microscopes are required at the most important steps. And the tools are sophisticated ? two mass spectrometers measure shell fragments for different isotopes of carbon and oxygen. (Isotopes are elements with varying numbers of neutrons. Heavier isotopes of oxygen in the shell material generally correspond to colder ocean temperatures.)

?Isotopes are just wonderful tracers in nature,? Wanamaker said, noting he also takes isotope measurements for research projects across campus and beyond.

When it comes to Wanamaker?s own work with clam shells, ?In the broadest sense, we?re trying to add to our understanding of oceans over the last several thousand years,? he said. ?We have a terrestrial record ? we can get an excellent chronology from tree rings and there is a climate signal there. But that?s missing 70 percent of the planet.?

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The above story is reprinted from materials provided by Iowa State University.

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Journal Reference:

  1. Alan D. Wanamaker, Paul G. Butler, James D. Scourse, Jan Heinemeier, J?n Eir?ksson, Karen Luise Knudsen, Christopher A. Richardson. Surface changes in the North Atlantic meridional overturning circulation during the last millennium. Nature Communications, 2012; 3: 899 DOI: 10.1038/ncomms1901

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Monday, October 1, 2012

Update: Sun in My Belly | Atlanta Food & Drink Blog | Omnivore ...

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89% Robot & Frank

All Critics (74) | Top Critics (31) | Fresh (66) | Rotten (8)

"Robot & Frank" hits all the right notes - romantic, fantastic, tragic and sweet.

There's a warm and poignant interplay between the co-stars.

Langella ... is tremendous.

It may not seem like an even playing field pitting an actor as powerfully intense as Frank Langella opposite a robot, but that's the game plan behind the waywardly endearing, slightly futuristic fantasy Robot & Frank.

Much of Robot & Frank is (frankly) resistible, including the climactic narrative twist, but there is also a likeable oddness that transcends the sentimental contrivance.

An endearing movie about a human and his mechanical new buddy.

... a marvel of the highest order. Robot and Frank manages to seamlessly blend comedy, science fiction and drama into a film that is hilarious, truly original and utterly heartfelt

This blend of sentiment and genre fancy is not unlike something Ray Bradbury might have contrived for The Magazine of Fantasy & Science Fiction.

Robot & Frank is an airy, engaging flight of fancy. It's also part caper film, part character study, and part allegory about aging. Robot & Frank shouldn't work, but it does.

..never hits the easy and obvious beats of a buddy comedy; there's no sentimental bonding between man and mecha man. Similarly, though it feints toward romance, the relationship ... resolves in an unexpectedly bittersweet way.

"Robot & Frank" is a study of a man who lives with his past mistakes but can't shake how truly alive they made him feel when he was making them, regardless of what they cost him.

Hodgepodge of moods built around an unlikely story of friendship between a man and his service robot, the film carries itself confidently, with occasional moments of significant emotion.

They get the robot right, with fluid movement (by dancer Rachael Ma) and canned warmth in its user-friendly voice (performed by Peter Sarsgaard).

What a weird, winning little movie is Robot & Frank.

The chief spectacle here -- and it's a good one -- is Langella in gruff, curdled mode, an underappreciated master actor slipping seamlessly into a bespoke role.

"Robot & Frank" is so endearing it's easy to forget it's science fiction.

The movie is sweet and agreeably unambitious, derailed only by an egregious third-act twist.

Frank Langella gives a terrific performance as the second of the two title characters in this modest but heartfelt science-fiction comedy.

There's no denying the, err, chemistry between Langella and his nameless buddy.

Amusing and ingratiating, leaving a bittersweet afterglow

Smart and sweet, Robot and Frank feels familiar while you're watching it yet consistently finds ways to catch you off-guard.

Further proof that sci-fi need not be high-budget spectacle, and can actually do a good little job exploring the human condition, our characters, and our memories.

Frank Langella's presence would be enough to pique my interest in any film. Robot & Frank offers him a modest starring vehicle with a science-fiction spin, and the result is one of the most enjoyable indie films of the year.

More Critic Reviews

Source: http://www.rottentomatoes.com/m/robot_and_frank/

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NYT: Supreme Court faces crucial rulings

The Supreme Court returns to the bench on Monday to confront not only a docket studded with momentous issues but also a new dynamic among the justices.

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The coming term will probably include major decisions on affirmative action in higher education admissions, same-sex marriage and a challenge to the heart of the Voting Rights Act of 1965. Those rulings could easily rival the last term?s as the most consequential in recent memory.

The theme this term is the nature of equality, and it will play out over issues that have bedeviled the nation for decades. ?Last term will be remembered for one case,? said Kannon K. Shanmugam, a lawyer with Williams & Connolly. ?This term will be remembered for several.?

The term will also provide signals about the repercussions of Chief Justice John G. Roberts Jr.?s surprise decision in June to join the court?s four more liberal members and supply the decisive fifth vote in the landmark decision to uphold President Obama?s health care law. Every decision of the new term will be scrutinized for signs of whether Chief Justice Roberts, who had been a reliable member of the court?s conservative wing, has moved toward the ideological center of the court.

?The salient question is: Is it a little bit, or is it a lot?? said Paul D. Clement, a lawyer for the 26 states on the losing side of the core of the health care decision.

The term could clarify whether the health care ruling will come to be seen as the case that helped Chief Justice Roberts protect the authority of his court against charges of partisanship while accruing a mountain of political capital in the process. He and his fellow conservative justices might then run the table on the causes that engage him more than the limits of federal power ever have: cutting back on racial preferences, on campaign finance restrictions and on procedural protections for people accused of crimes.

It is also possible that the chief justice will become yet another disappointment to conservatives, who are used to them from the Supreme Court, and that he will join Justice Anthony M. Kennedy as a swing vote at the court?s center. There is already some early evidence of this trend: in each of the last three terms, only Chief Justice Roberts and Justice Kennedy were in the majority more than 90 percent of the time.

?We all start with the conventional wisdom that Justice Kennedy is going to decide the close cases,? said Mr. Clement, who served as United States solicitor general under President George W. Bush. ?We?ve all been reminded that that?s not always the case.?

The texture of the new term will be different, as the court?s attention shifts from federalism and the economy to questions involving race and sexual orientation. The new issues before the court are concrete and consequential: Who gets to go to college? To get married? To vote?

First up
On Oct. 10, the court will hear Fisher v. University of Texas, No. 11-345, a major challenge to affirmative action in higher education. The case was brought by Abigail Fisher, a white woman who says she was denied admission to the University of Texas based on her race. The university selects part of its class by taking race into account, as one factor among many, in an effort to ensure educational diversity.

Just nine years ago, the Supreme Court endorsed that approach in a 5-to-4 vote. The majority opinion in the case, Grutter v. Bollinger, was written by Justice Sandra Day O?Connor, who said she expected it to last for a quarter of a century.

But Justice O?Connor retired in 2006. She was succeeded by Justice Samuel A. Alito Jr., who was appointed by Mr. Bush and who has consistently voted to limit race-conscious decision making by the government. Chief Justice Roberts, another Bush appointee, has made no secret of his distaste for what he has called ?a sordid business, this divvying us up by race.?

Justices Kennedy, Antonin Scalia and Clarence Thomas all dissented in the Grutter case, and simple math suggests that there may now be five votes to limit or overturn it.

The reach of such a decision could be limited by the idiosyncrasies of the admissions system in Texas. The university provides automatic admission to students in Texas who graduate in roughly the top 10 percent of their high school classes. That approach generates substantial diversity, partly because many Texas high schools remain racially homogeneous.

Ms. Fisher narrowly missed the cutoff at a high school whose students have above-average test scores for the state. She was rejected for one of the remaining spots under the part of the admissions program that considers applicants? race.

The court may uphold the Texas system under Grutter, or it may rule against it on narrow grounds by saying, for instance, that race-conscious admissions are forbidden where a race-neutral method ? like the 10 percent program ? can be said to be working.

But the court may also follow the health care ruling with a second landmark decision, this one barring racial preferences in admissions decisions altogether. Given persistent achievement gaps, even after controlling for family income, such a ruling would make the student bodies of many colleges less black and Hispanic and more white and Asian.

The court will probably also take on same-sex marriage. ?I think it?s most likely that we will have that issue before the court toward the end of the current term,? Justice Ruth Bader Ginsburg said at the University of Colorado on Sept. 19.

She was referring to challenges to an aspect of the federal Defense of Marriage Act, which bars the federal government from providing benefits to same-sex couples married in states that allow such unions. The federal appeals court in Boston struck down that part of the law, and both sides have urged the court to hear the case. More than 1,000 federal laws deny tax breaks, medical coverage and burial services, among other benefits, to spouses in same-sex marriages.

'We are now a very different nation'
The justices will also soon decide whether to hear a more ambitious marriage case filed in California by Theodore B. Olson and David Boies. It seeks to establish a federal constitutional right to same-sex marriage.

Chief Justice Roberts has not yet voted in a major gay rights case. Justice Kennedy wrote the majority opinions in both Lawrence v. Texas, a 2003 decision that struck down a Texas law making gay sex a crime, and Romer v. Evans, a 1996 decision that struck down a Colorado constitutional amendment that banned the passage of laws protecting gay men and lesbians. Most observers see him as the decisive vote in same-sex marriage cases.

The justices are also quite likely to take another look at the constitutionality of a signature legacy of the civil rights era, the Voting Rights Act of 1965. In 2009, the court signaled that it had reservations about the part of the law that requires the federal review of changes in election procedures in parts of the country with a history of discrimination, mostly the South.

?We are now a very different nation? than the one that first enacted the Voting Rights Act, Chief Justice Roberts wrote for himself and seven other justices. ?Whether conditions continue to justify such legislation is a difficult constitutional question we do not answer today.?

The chief justice seemed to invite Congress to revise the law, but lawmakers have taken no action.

Challenges to the law have arisen in several lawsuits in the current election season, including ones concerning redistricting and voter identification requirements.

?It will be interesting to see if the justices worry half as much about the emerging restrictions on voting as they worried about restrictions on political spending,? said Pamela S. Karlan, a law professor at Stanford.

On Monday, the new term will start with a case of great interest to business groups, Kiobel v. Royal Dutch Petroleum, No. 10-1491. The case was brought by 12 Nigerian plaintiffs who said the defendants, foreign oil companies, had been complicit in human rights violations committed against them by the Abacha dictatorship in Nigeria. The question in the case is whether American courts have jurisdiction over such suits, and business groups are hoping the answer is no.

In the last term, business groups achieved a series of victories, often by lopsided majorities. In cases with an individual on one side and business interests on the other, the court ruled for the business side 12 out of 14 times, according to calculations by Lauren R. Goldman, a lawyer with the firm Mayer Brown. In the two previous terms, the number of business cases was comparable, but individuals won at least half of the time.

Introducing himself to the nation at his confirmation hearings in 2005, Chief Justice Roberts said that ?judges are like umpires? in that they do not make the rules but merely apply them.

?Nobody ever went to a ballgame to see the umpire,? he said.

But the calls Chief Justice Roberts made in the health care case were surprising enough that it will be hard to look away. He voted with the court?s conservatives to say that the law was not authorized by Congress?s power to regulate interstate commerce and then joined the court?s liberals to say it was authorized by Congress?s power to levy taxes. No other justice joined every part of his controlling opinion.

Charles Fried, who served as solicitor general in the Reagan administration and filed a brief in support of the law, said the reasoning in the health care decision was mystifying enough to foreclose predictions about the future of the Roberts court.

?This is a court that under Chief Justice Roberts called a ball a strike, a strike a ball, but got the batter to base where he belonged,? said Professor Fried, who teaches at Harvard Law School. ?So who knows what to expect.?

This story, "Supreme Court Faces Crucial Rulings in Coming Term," originally appeared in The New York Times.

Copyright ? 2012 The New York Times

Source: http://www.msnbc.msn.com/id/49224738/ns/us_news-the_new_york_times/

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